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Development of the SDI(Site-Direct-Integration) System for gene replacement |
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| Hiroyasu Ebinuma, Kazuya Nanto,Keiko Yamada-Watanabe (Foresty Science Research Lab. Nippon Paper Industries Co.,LTD.) |
World Congress on Invitro Biology |
| May 23,2004 San Francisco, USA
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Abstract:
Roughness and compressibility of paper surface are known to important factors for the missing dot issue during gravure printing. However, in most cases, only smoothness is measured for these grades. In this research, an ultra low load indenter is used to evaluate the compressibility of small points within the sample. The indenter is able to measure the modulus of the paper surface at different loading rates and loading forces with a lengthscale of less than 0.1 mm. Coating layers with a range of binder types and pigments are applied to a woodfree base, a wood containing base, and sized basepapers. The samples are characterized in terms of compressibility and roughness. Roughness is measured with both air leak methods and a mechanical stylus. A supercalendered (SC) grade is also tested. Samples are printed with the Heliotest in the laboratory to evaluate missing dots. A model is proposed, that describes both roughness and compression, that may be able to predict roto-gravure print quality. The results show some correlation between roughness and missing dots, but compressibility of the surface can be just as important. The rough but compressible SC paper had the best performance in terms of missing dots. Air-leak roughness tests tend to group samples according to the base, but the mechanical stylus tends to give a good result for a range of bases. A large reduced modulus of the surface if found to promote missing dots. This result shows that poor compressibility is a factor in the missing dot issue. Model parameters are correlated with the indenter tests. The model predicts the occurrence of contact between the paper and the inside plane of a gravure cell in the printing event.
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